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The FDA issued a drug safety communication about nonsteroidal anti-inflammatory drug (NSAID) use during pregnancy, mandating that product labels include warnings about risk of a rare but serious kidney complication in infants.

Use of over-the-counter or prescription pain medications — including aspirin, ibuprofen, naproxen, diclofenac, and celecoxib — after 20 weeks of pregnancy could potentially cause fetal kidney problems resulting in low levels of amniotic fluid and pregnancy complications, the agency said.

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