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Johnson & Johnson (JNJ)’s Bengay and Sanofi (SAN)’s Icy Hot are among topical pain relievers that have been associated with a rare risk of serious burns, U.S. regulators said today.

The over-the-counter pain-relieving creams, lotions and patches are linked to 43 cases of burns on the application site, the Food and Drug Administration said in a safety announcement. The cases were identified in a search of the FDA’s adverse event reporting system and medical literature.

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