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Sorin SpA (SRN) fell the most in almost five years in Milan trading after Forbes reported that potentially fatal blockages have developed in the company’s Mitroflow heart valve when used in children.

A girl who had a Mitroflow valve died last year during a severe gastrointestinal illness, and an examination revealed that the device was severely obstructed, surgeons at Boston Children’s Hospital said in a Jan. 14 letter to the American College of Cardiology. An echocardiogram seven months before she died found no signs of blockage, according to the letter, which was reported on Forbes.com on Jan. 21.

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